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(K) Principle Component Analysis compiling all motor function scores from SPF-WT, SPF-ASO, GF-WT, and GF-ASO cohorts (J) Percent water content in fecal pellets from 12-13 week old animals (I) Total fecal pellets produced in 15 minutes by 24-25 week old animals (H) Time course of fecal output in a novel environment over 15 minutes by 24-25 week old animals (G) Body weight of 24-25 week old animals (F) Hindlimb clasping reflex scores by 24-25 week old animals (E) Time to removal adhesive from nasal bridge by 24-25 week old animals

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(D) Time to descend pole by 24-25 week old animals (C) Time to traverse beam by 24-25 week old animals

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(B) Time to fall from inverted grid by 12-13 week old animals (A) Body weight of 12-13 week old animals

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Body weight of SPF and GF animals, and analysis of aged mice Related to Figure 1.

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